GREENVILLE, South Carolina — The death of the actress Hayden Panettiere, the star of Heroes and Nashville, has been ruled accidental, ending the local police investigation into how she died, police in South Carolina have said. “Based on the Medical Examiner’s determination and the findings of the investigation, Hayden Panettiere’s death has been ruled accidental,” the Greenville Police Department said in a statement reported by the BBC. Panettiere died in August, at the age of 36, from the toxic effects of fentanyl, Xanax and several other drugs in her system.
August 16
Panettiere was found unresponsive at a home in Greenville on August 16, after first responders were called to a report of a woman in cardiac arrest. She was pronounced dead at 36, a former child star who had been on screen since she was 11 months old. Her family confirmed the death, and a preliminary report found no signs of foul play. In the weeks that followed, authorities waited on toxicology results while the circumstances of the death were investigated — an inquiry that the BBC reported the US Drug Enforcement Administration also joined, through its US media partner CBS News. Whether the federal inquiry has also concluded is unclear; the BBC said it had contacted the DEA for comment.
What The Coroner Found
In September, the Greenville County Coroner’s Office confirmed that Panettiere died from the combined toxic effects of five substances: fentanyl, a powerful synthetic opioid; alprazolam, sold under the brand name Xanax; quetiapine, an antipsychotic medication; methocarbamol, a prescription muscle relaxant; and 4-ANPP, a chemical associated with fentanyl. An autopsy found no physical injuries or signs of trauma that contributed to her death, and the coroner’s office ruled the death an accident. Wednesday’s police statement closes the local file on the same basis: the medical examiner’s determination, and the findings of the department’s own investigation.
The Career
Panettiere first appeared on screen at 11 months old, in a 1990 toy commercial; by the age of five she had appeared in more than 50 commercials. Her first major roles came in the daytime soaps One Life to Live (1994–1997) and Guiding Light (1996–2000), where her character’s leukemia storyline drew a special recognition award from the Leukemia & Lymphoma Society. She was the voice of Princess Dot in A Bug’s Life (1998) — earning a Grammy nomination for its read-along album — and played Sheryl Yoast in Remember the Titans (2000). Wide recognition came as Claire Bennet, the indestructible cheerleader of NBC’s Heroes (2006–2010), a role that won her a Saturn Award. She played Kirby Reed in Scream 4 (2011) and returned for Scream VI (2023), and spent six seasons as the country singer Juliette Barnes in Nashville (2012–2018), earning two Golden Globe nominations; she also voiced Kairi in the Kingdom Hearts games. Her final film, the thriller Sleepwalker, in which she starred and served as executive producer, was released this year, and her memoir, This Is Me: A Reckoning, was published in 2026.
What She Spoke About
Panettiere had spoken publicly, over many years, about her struggles with addiction and with postpartum depression after the birth of her daughter, Kaya, in 2014 — and about giving up custody to Kaya’s father, the former heavyweight boxing champion Wladimir Klitschko, in 2018, as she dealt with both. Klitschko, in a statement after her death, wrote: “She built an incredible career through immense talent, while also facing the darker sides of a very demanding industry… Rest easy, Hayden. May you find eternal peace.” Her death came three years after that of her younger brother, the actor Jansen Panettiere, who died in 2023 at the age of 28 of an enlarged heart. She is survived by her daughter.
The Ruling — In Short
Greenville police have concluded their investigation into Hayden Panettiere’s death and ruled it accidental, following the medical examiner’s determination. The Heroes and Nashville star, 36, was found unresponsive at a Greenville home on August 16; the coroner found she died from the toxic effects of fentanyl, alprazolam (Xanax), quetiapine, methocarbamol and 4-ANPP, with no injuries contributing. The DEA reportedly joined the local investigation; whether the federal inquiry has concluded is not known.
Sources: BBC News; People; Rolling Stone; Newsmax — reporting of October 28–29, 2026, and of the Greenville County Coroner’s findings in September 2026.

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